samedi 31 août 2019

LOTS OF VITAMIN D , DOES IT HELP BUILD BONES IN HEALTHY PEOPLE NO NO NO

As an endocrinologist, I believe that we must give hormones or supplements to people who demonstrate a definite deficiency and not on some empirical treatment that more may be better when a need in the body does not exist.
Vitamin D which is a hormone is one such case in point. There has been a plethora of supposed benefits to Vitamin D but on closer examination none of which has proven to be of benefit to non deficient healthy people.
I tell my patients: if you are low in Vitamin D go for a walk for 20 minutes a day, your vitamin D levels would come up. I realized that among the indigenous peoples that I work with not a single person had NORMAL vitamin D levels as proscribed by the scientists. there must be something more to it, I thought. 
If you are a true indigenous person(just card carrying wont do) the chances of you having osteoporosis is small, change of life is accepted as a normal passage of life, so get out in the sun and walk a little..
Here is a recent article on high vitamin D supplementation.



Original Investigation
August 27, 2019

Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone StrengthA Randomized Clinical Trial

JAMA. 2019;322(8):736-745. doi:10.1001/jama.2019.11889
Key Points
Question  Does higher-dose vitamin D supplementation improve bone mineral density (BMD, measured using high-resolution peripheral quantitative computed tomography) and bone strength (measured as failure load)?
Findings  In this randomized clinical trial that included 311 healthy adults, treatment with vitamin D for 3 years at a dose of 4000 IU per day or 10 000 IU per day, compared with 400 IU per day, resulted in statistically significant lower radial BMD (calcium hydroxyapatite; −3.9 mg HA/cm3 and −7.5 mg HA/cm3, respectively); tibial BMD was significantly lower only with the daily dose of 10 000 IU. There were no significant differences in bone strength at either the radius or tibia.
Meaning  Among healthy adults, supplementation with higher doses of vitamin D did not result in improved bone health; further research would be needed to determine whether it is harmful.

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