mercredi 16 octobre 2013

CAMEL MILK.. A NATURAL ANTI-DOTE TO DIABETES, OF COURSE IN CONTEXT

CAMEL MILK. A NATURAL ANTI-DOTE TO DIABETES, OF COURSE IN CONTEXT
BioMed Central is an extraordinarily wide and comprehensive source of cutting edge research and investigations from around the world. These peer reviewed articles are published very quickly so that interested parties around the world could easily become aware of what is going on in the world of science, investigation, public health and complementary medicine.
Camel milk ameliorates steatohepatitis, insulin resistance and lipid peroxidation in experimental non-alcoholic fatty liver disease (NAFLD)
Research from College of Medicine at King Saud University in the Kingdom of Saudi Arabia
BMC Complementary and Alternative Medicine 2013,13:264 doi:10.1186/1472-6882-13-264
Published: 13 October 2013
The rats fed high cholesterol diet without Camel Milk developed features similar to those of non-alcoholic steatohepatitis (NASH), characterized by hepatic steatosis; inflammatory cellular infiltration in liver tissue; altered liver functions; and increased total cholesterol, triglycerides, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol, atherogenic index (AI), blood glucose, insulin resistance (IR), and malondialdehyde (MDA) levels. Additionally, feeding this diet to animals decreased catalase (CAT) activity and the glutathione (GSH) and high-density lipoprotein (HDL) cholesterol levels. Camel milk intake for eight weeks decreased hepatic fat accumulation and inflammatory cellular infiltration, preserved liver function, increased the GSH levels and CAT activity, decreased the MDA levels, and ameliorated the changes in the lipid profile, AI, and IR in animals from the High Cholesterol plus Camel Milk Group.

Camel Milk has a unique composition that is rich in minerals; vitamins, insulin and insulin-like protein, and it increased HDL-cholesterol and ameliorated the biochemical and cellular features of NAFLD in rats that received a High Cholesterol diet. The antioxidant effect of CM is a likely mechanism for the altered metabolism and absorption of High Cholesterol diet in the presence of Camel Milk. Regular consumption of Camel Milk could provide a natural way to protect against NAFLD induced by a high-fat diet.
I wrote to the lead author who was kind enough to reply immediately.
“Although the number of large population studies about the effects of Camel Milk in Diabetes are still limited, Agarwal et al (2007) reported zero prevalence of Diabetes Mellitus among the Rica Community in India. These are camel breeders who depend markedly on camel milk on their diet”. The kind doctor provided further articles on the efficacy of camel milk, some under clinical settings.

Why did this article seem so important? NAFLD or fatty liver has drawn some attention in the west as well as in Asia.
In a study from Malaysia, 68% of Indians, 65 % of Malay (both Men) and 5.2% Chinese women were found to have Fatty Liver.
In the USA, it is estimated that one in five adults have fatty liver and that Mexicans living in America as well as Obese people have higher than normal rate of Fatty Liver.
What causes Fatty Liver? As proven in the experiment above, you can induce Fatty Liver by a High Cholesterol Diet.
I would think that, it is very similar to
The Western pattern diet, also called Western dietary pattern or the meat-sweet diet, is a dietary habit chosen by many people in some developed countries, and increasingly in developing countries. It is characterized by high intakes of red meat, sugary desserts, high-fat foods, and refined grains. It also typically contains high-fat dairy productshigh sugar drinks and higher intakes of processed meat.

During my repeated visits to Malaysia and during participatory observation, there is no doubt that the local Chinese ate better quality food than the Indians or the Malays, which may be reflected in their fatty liver rates.

NAFLD was strongly associated with Diabetes Mellitus, Impaired Glucose Tolerance, BMI greater than 23, Decreased HDL, Increased Triglycerides and Hypertension. This association has been proven over and over again from various epidemiological studies including the recent one from NHANES (epidemiological) study in the USA.

This also ties in nicely with the thought that Fatty Liver comes before Diabetes and that Diabetes Mellitus Type 2 which is now spreading like fire may be due an organ failure at the level of LIVER rather than pancreas or Muscles as it is conventionally thought.
So an article from those indefatigable researchers at Helsinki in the October 2013 issue of Diabetologia was a revelation indeed. It made such an impact in the media that all TV channels and major newspapers picked it up. Even the drug company supported “Medical Journals” which are sent free to doctors were full of enthusiasm about this news, licking their chops at the dream of manufacturing some highly priced anti-inflammatory medications
HEALTHY OBESE LIVER ON THE LEFT, UNHEALTHY OBESE LIVER ON THE RIGHT
New York Times of 9 October 2013
They are a mystery to researchers: people who are significantly overweight and yet show none of the usual metabolic red flags. Despite their obesity, they have normal cholesterol levels, healthy blood pressure levels and no apparent signs of impending diabetes.
Researchers call them the metabolically healthy obese, and by some estimates they represent as many as a third of all obese adults. Scientists have known very little about them, but new research may shed some light on the cause of their unusual metabolic profile.
A study in the journal Diabetologia has found that compared with their healthier counterparts, people who are obese but metabolically unhealthy have impaired mitochondria, the cellular powerhouses that harvest energy from food, as well as a reduced ability to generate new fat cells.
Unlike fat tissue in healthy obese people, which generates new cells to help store fat as it accumulates, the fat cells of the unhealthy obese swell to their breaking point, straining the cellular machinery and ultimately dying off.
This is accompanied by inflammation, and it leads to ectopic fat accumulation — the shuttling of fat into organs where it does not belong, like the liver, heart and skeletal muscle. A fatty liver frequently coincides with metabolic abnormalities, and studies suggest that it may be one of the causes of insulin resistance, the fundamental defect in Type 2 diabetes.
In the healthy obese, however, the fat tends to remain in the subcutaneous padding just beneath the skin, where it appears to be fairly innocuous.
“The group that doesn’t gain fat in the liver as they get obese seems to avoid inflammation and maintain their metabolic health,” said Dr. Jussi Naukkarinen, a research scientist specializing in internal medicine at the University of Helsinki. “There is a complete difference in how they react to obesity.
So, kudos to our desert brethren who continue to drink Camel Milk and pity those who flock to the McDo and other Disease Mongers now lining the air conditioned malls of the Middle East and the Gulf (Almost all countries in the Gulf region can be included in the Fattest on the Earth List)

Everything will now come down to Inflammation in the body and the modern diseases being a manifestation of it.
And the mind body connection will be further investigated by the news that a combination of Serotonin and Epinephrine activation increases fat burning, helping the organism to loose weight. It would tie in with Autonomic nervous system, and then with the Eastern Philosophy… the possibilities are endless.